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Study: Medicines, frequent counseling helps cancer patients quit smoking

Oct. 13 (UPI) — A program that included telephone counseling sessions and one of two smoking cessation drugs was 50% more effective than telephone consultations alone at helping cancer patients quit smoking, a study published Tuesday by JAMA found.

Among cancer patients who underwent treatment with four bi-weekly and three monthly counseling sessions by telephone and either bupropion, marketed as Wellbutrin, or varenicline, marketed as Chantix, for up to six months, 35% were able to successfully quit smoking, the data showed.

But only 22% of the cancer patients who underwent treatment with the telephone counseling sessions had successfully quit after six months, according to the researchers.

“Counseling plus medication is the state-of-the art tobacco treatment for cancer patients,” study co-author Elyse R. Park told UPI.

“Smoking cessation assistance should be an integral part of cancer care and sustained tobacco support can be effective for cancer patients who smoke,” said Park, an associate professor of psychiatry at Harvard Medical School.

More than 34 million adults in the United States smoke, and some 16 million are living with smoking-related diseases, including cancer, according to the Centers for Disease Control and Prevention.

Up to 20% of cancer survivors continue to smoke, despite the fact that quitting improves prognosis with the disease, research suggests.

For their study, Park and her colleagues evaluated smoking cessation treatment programs in 303 adults recently diagnosed with breast, gastrointestinal, genitourinary, gynecological, head and neck, lung, lymphoma or melanoma cancers.

Roughly half — 153 — underwent “intensive” treatment for smoking, with telephone counseling and their choice of bupropion or varenicline, with the rest receiving “standard” care, with telephone counseling only, for up to six months, the researchers said.

Both bupropion and varenicline have been approved for smoking cessation treatment by the U.S. Food and Drug Administration.

The most common adverse events in the two treatment groups were nausea, rash, hiccups, mouth irritation, difficulty sleeping and vivid dreams, and all were more common in the patients who received “intensive” care, the researchers said.

“Nausea is a side effect of varenicline, so [its use] should be monitored for patients who are experiencing nausea from their cancer treatment,” Park said.

In addition, patients on tamoxifen for breast cancer should not take bupropion, or receive a reduced dose, because of interactions between the two drugs, she said.

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Genprex to Present at the Alliance for Regenerative Medicine’s Virtual Cell and Gene Meeting on the Mesa

Genprex, Inc. (“Genprex” or the “Company”) (NASDAQ: GNPX), a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes, today announced that it will be presenting at the Alliance for Regenerative Medicine’s (ARM) virtual Cell and Gene Meeting on the Mesa, taking place October 12-16, 2020. Michael Redman, Executive Vice President and Chief Operating Officer of Genprex, will lead the company’s presentation.

The 2020 Cell and Gene Meeting on the Mesa will be delivered in a virtual format over the course of five days where attendees will be able to watch company presentations on-demand, in addition to two live-streaming panels each day. The Cell and Gene Meeting on the Mesa is the sector’s foremost annual conference, bringing together senior executives and top decision-makers in the industry to advance cutting-edge research into cures. Tackling the commercialization hurdles facing the cell and gene therapy sector today, this meeting covers a wide range of topics from clinical trial design to alternative payment models to scale-up and supply chain platforms for advanced therapies.

For more information on the conference, or to register, please visit https://www.meetingonthemesa.com.

About Genprex, Inc.

Genprex, Inc. is a clinical-stage gene therapy company developing potentially life-changing technologies for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new treatment options for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. The Company’s lead product candidate, GPX-001 (quaratusugene ozeplasmid), is being evaluated as a treatment for non-small cell lung cancer (NSCLC). GPX-001 has a multimodal mechanism of action that has been shown to interrupt cell signaling pathways that cause replication and proliferation of cancer cells; re-establish pathways for apoptosis, or programmed cell death, in cancer cells; and modulate the immune response against cancer cells. GPX-001 has also been shown to block mechanisms that create drug resistance. In January 2020, the U.S. Food and Drug Administration granted Fast Track Designation for GPX-001 for NSCLC in combination therapy with osimertinib (AstraZeneca’s Tagrisso®) for patients with EFGR mutations whose tumors progressed after treatment with osimertinib alone. For more information, please visit the Company’s web site at www.genprex.com or follow Genprex on Twitter, Facebook and LinkedIn.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding the effect of Genprex’s product candidates, alone and in combination with other therapies, on cancer and diabetes, regarding potential, current and planned clinical trials, regarding the Company’s future growth and financial status and regarding our commercial partnerships and intellectual property licenses. Risks that contribute

Medicine’s Changing View Of Racism Towards Healthcare Professionals

Almost a decade ago, I was subject to a racist tirade by a patient.

The patient told me, “Why don’t you go back to India?”  

I responded angrily to the patient: “Why don’t you leave this [expletive] hospital?” 

I sought guidance on how to cope with and respond to the patient’s racism and found little.  The institution at which I worked had no policies in place that guided my response.

I had the patient’s care reassigned to other physicians and subsequently wrote about my experience and reflections in an essay called, “The Racist Patient,” that was published in the Annals of Internal Medicine and featured in the New York Times.

My conclusion: there were limits to service and the abuse to which we might accept as healthcare professionals.

The essay generated controversy and drew two different kinds of responses.

The first set of responses was from sympathetic physicians with like experiences who felt unprotected by the institutional cultures in which they worked.  

I heard from an African American physician whose hospital routinely reassigned patients from his care so as to not compromise their patient satisfaction results.

I heard also from a pharmacist whose management accommodated a patient request to not have “that Paki touching [their] meds or speaking to [her] about them so make sure the other pharmacist is available.”  

One Vietnamese-American academic physician wrote:

“I am of Vietnamese-descent and your article had a resounding impact on me.  I have experienced such overt racist and sexist comments in my career made so much more difficult when it is directed at me as an attending physician and in front of my residents.”

The second, more dominant set of responses was from physicians who held the view that healthcare professionals are somehow held to a higher ethical standard, that the unwritten code of professionalism requires us to ignore our own feelings and continue to care for patients regardless of their views.

One physician wrote an extensive letter to me in response:

“The tone and words in your article demonstrate to me that you have a long way to travel, not to India or anywhere else, but to a place in your heart that tells you that being a good doctor means that patients, even difficult patients, deserve better treatment than that which you gave to [the patient]….But upon further reflection you arrogantly felt justified in not apologizing to him because ‘there are clear limits’ to your service. Yes, doctors are not slaves, submitting to any kind of abuse but your….response was not professional.”

Another physician wrote a published letter to the Annals of Internal:

“His complaint was legitimate…You missed an opportunity to heal and win over a fellow man.”

I certainly regretted my angry instinctual initial response—but also felt that the traditional institutional perspective on abusive, racist patients is medicine’s own version of “the customer is always right.” Being a medical

Wholesome Diets, Medicines, Ailments, & Conditions

Medication that affect gastrointestinal perform could also be additional categorized as medicine for the remedy of peptic ulcer, anti-diarrheal, laxatives, digestants, and anti-emetics. Treatment consisted of giving the affected person an emetic to induce vomiting, or they would take away excess blood.

Exams which are performed on animals range from them being compelled to ingest completely different family cleansing merchandise and then monitored to see the outcomes and new cosmetics positioned on their pores and skin to seek out out if there are any negative effects that would be dangerous to a human.

On the flipside, the consumerist mannequin is where consumers have excessive control over their therapies while physicians have low management – think about sufferers now being able to seek second opinions, choose their docs, have interaction in alternative and biomedical treatments on the similar time.

Maintain them in front of you and focus on the stability of your male self (right)and your female self left(left)and observe silently the connection or lack of connection between the feminine and the male and above, To assist steadiness them you may call upon the medicine of the creature separately Be sure to enter the silence and permit the animal to speak.

But in Roman occasions it was much more important, and the amount of things the folks did with olive oil may very well be stunning. Now that you’ve got a greater understanding of the plant sources of medicine, let’s transfer on to the animal and mineral sources. Decide the shoppers present treatment is efficient for the pain relief particularly if the affected person has taken the ache medicine all day with no relief.…

Allopathic Medicines In Our Each day Life

Oils used as medication might be separated into two varieties: fixed and risky. If we will justify that different people feel pain, why is it stated that animals do not really feel ache? The blood lets a physician evaluate a affected person’s well being. With the alarming rate of death due to the dengue virus in this tropical country, the Division of Well being issued an advisory: “Never trust the medical treatment found on tawa-tawa plant.

It is very important seek the advice of a health care provider before pursuing homeopathic medicines as the therapy is individualized and based mostly on the medical historical past of the affected person, lifestyle, weight loss program and emotional state.

It is rather important that you simply ask your patient every time if they are in ache. There are even some practices the place animals are forced to ingest a medicine before it is put available on the market to make sure that there aren’t any life- threatening illnesses that will likely be brought on to a human from taking the product.

He was administered with blood transfusion but my mother requested that she be allowed to let him drink the boiled juice of Tawa-tawa. These are all body painkiller medicines. For many people, the blood thickens as the physique attempts to deal with the intense warmth, and nosebleeds and swollen ankles are common for those unused to the Greek summer time.

Verify the sufferers within the household’s data of the uncomfortable side effects and security cautions of the pain drugs that they are taking, equivalent to not driving or utilizing heavy equipment while taking. Every medicine card has a number and a picture of an animal on its face.…

Allopathic Medicines In Our Daily Life

He was administered with blood transfusion however my mom requested that she be allowed to let him drink the boiled juice of Tawa-tawa. These are all body painkiller medicines. For many people, the blood thickens as the physique attempts to cope with the intense warmth, and nosebleeds and swollen ankles are common for those unused to the Greek summer time.

Animal cruelty is fallacious but what about all those individuals now we have locked up because they have accomplished one thing fallacious we must always use them for our resurch in stead of animals. Alternatively when medicine failed and the patient died, their body was washed in anointed in scented oil earlier than being laid to rest.

Medicine and Radiology :- It’s a specialisation involved with the non-surgical medical features of is involved with major diagnosis and remedy of oral ailments that do not respond to traditional dental procedures.Radiology offers with the radiographs(x-rays) of teeth and their related structures.

Tranquillizers are the medicines which induce or carry the sleeping condition of the physique. Crucial Stage – is when a affected person experiences chest pain, blood shock and bleeding. We can avoid the poisonous effects of artificial medicine that we used to buy within the drug retailer by benefiting on the benefits of natural home remedies.

Infrared in Health care – Digital Infrared Thermal Imaging (DITI) is a technique that’s used for analysis in the medical subject. Freiberg’s disease, which is an osteochondritis of the metatarsal head, causes ache on weight bearing or compression. These anti-allergy medicines could be consumed within the type of tablets, syrups, powder and drops.…

Wholesome Diets, Medicines, Ailments, & Circumstances

2 South card describes how animal medicine is teaching the kid within you or your grownup self. Like all medicines produced immediately potential side-effects can develop into obvious with excessive use. Plan nursing care resembling dressing adjustments, showers, ambulation when the patient is comfortable and has been given a ache medication about 30 min.

They tend to look apart from the info that animals have given thousands and thousands around the globe a new outlook on life, and would quite see solely the destructive uncomfortable side effects of animal testing which far outweighs the optimistic issues animal testing has contributed to the medical world.

They loved the status of free citizens and one in every of their quantity, Galen (Latin title Claudius Galenus, c. ADVERT 130-201), combined the speculation of the humours along with his own studies in anatomy and physiology to supply a complete medical encyclopedia, which remained an ordinary reference for greater than a thousand years although his anatomical descriptions, which have been based mostly on dissections he had carried out on animals, had been riddled with errors.

Do animals really feel the same pain that we as humans feel? In the acute care settings resembling medical, surgical, pediatrics, or labor and supply, you will come across every kind of individuals which might be in acute ache for a lot of totally different causes.

Considering these coronary heart and blood vessel situations are sometimes linked with poor health in addition to elevated physique weight, the user could really feel a double-effect from these doubtlessly harmful unwanted side effects. Hepatitis B virus is transmitted by blood and body fluid.…

Healthy Diets, Medicines, Illnesses, & Situations

The concept particular ailments required particular treatments was pioneered by the Swiss doctor and alchemist, Philippus Aureolus Paracelsus (real identify Theophrastus Bombastus von Hohenheim, 1493-1541), who additionally introduced the usage of chemical substances into medicine, pioneering the usage of mercury and laudanum.

Sulfonylureas group of medicines help the body to make more or required insulin. The side effects of Steroid medicines are weakening bones, thinning of skin and rising blood sugar stage. Water: As I discussed, biotin is a water-soluble vitamin, so drink tons and many water—health authorities advocate two liters, or eight cups, a day usually.

Patients are inspired to drink lots of water to keep the body’s water at an optimum degree. In order for better medicines and treatments to be developed, there must be a testing completed to make sure that the medicine will not be harmful or will not kill human.

These medicines block the transport of calcium into the smooth cells lining the coronary arteries and other arteries of the body. handout written material on a drugs that sufferers are taking to include side effects and different drug interactions.

Tranquillizers are the medicines which induce or carry the sleeping condition of the body. Critical Stage – is when a affected person experiences chest ache, blood shock and bleeding. We will avoid the poisonous effects of artificial medicine that we used to purchase within the drug store by benefiting on the benefits of natural house cures.…

Allopathic Medicines In Our Day by day Life

This may appear crazy but I never had no downside with my hair till I used biotin each time I wash my hair I observed that I m shedding some on the drain and my hair appears to be like less then it was.I am stopping it and I’m not going dangerous. For a long time standard medicine snubbed this remedy.

Infrared radiation is used in thermotherapy which finds broad application within the treatment of high blood pressure, arthritis, coronary heart failure, continual fatigue, stress, toxicity, insomnia, pain reduction, excessive cholesterol, accidents, diabetes, muscular pain etc., with the assistance of infrared saunas.

Many individuals flip to CAM due to adversarial results of pharmaceutical medication. I didn’t know that the folks before me had animals with mange & knew about the fleas, so I shrugged it off & bought Front Line & now they are all dropping fur & have pink spots, they are warm to the touch.

These medicines are containing iron compounds equivalent to Ferrous Gluconate, Ferric Ammonium Citrate and Iron Choline Citrate with Protein Hydrolysate, vitamin C and vitamin B advanced. Usually people are seen using Complementary and various medicine together with Western medical treatment programs in treating illnesses for getting higher results.

Hepatitis B virus has developed resistance to medicine like interferon, lamivudine, fevoir and extra, in accordance with Dr. Steven-Huv Han. It is a illness that causes the physique to supply too many crimson blood cells or platelets. Take your straight edge and pencil and draw a rectangle roughly 10 inches by 2 inches on on the leather-based piece you might be utilizing to create your medicine bag.…

Allopathic Medicines In Our Every day Life

Most of the antibiotics are combined with anti-allergic medicines like cetirizine Hydrochloride and chlorpheniramine maleate to get good consequence and to make sure our security. Vitamin B12 ( Cyanocobalamine ) is obtained from animal half and used for having good physique well being and extensively utilized in injection type.

I do not intend to seize the glory due Dr. Arturo V. Estuita, MD, a Filipino internist and chelationist, who has provide you with the scientific proof that the virus causing Hepatitis B can be managed within the bothered affected person. Ingesting that much water each day can even have very very bad uncomfortable side effects.

Clotrimazole, Beclomethasone Dipropionate, Gentamycin Sulphate, Iodochlorhydroxyquinoline, Chlorocresol, Benzyl Alcohol, Methyl paraben and Propyl barapen are a number of the medicines used in the manufacturing of Pores and skin lotions to get rid of pores and skin infections.

Authorities is hiding all of this from the folks trigger i bet if a video of animals being tortured was placed on TV individuals would feel unhealthy and vote towards animal cruelty unless they have no heart. From millions of virus in a Hepatitis B affected person the inhabitants of virus was diminished to only hundreds after remedy with infusion chelation remedy.

The mutuality model is where both physicians and patients have high control over medical remedy. Hey i’m a males 32 years old and have hair loos i have extrem ache in urine taking biotin a thousand three time a day have some stones to. In animals, the crops berries are dried and have proven to have antiviral proteins (PAP) that can enhance the immune system and counteracting cancerous tumors.…