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Fitness instructor, 41, pushes for mammogram, discovers breast cancer

Turning 40 meant getting a first mammogram for Heather Harrington, so she was surprised when her doctor told her not to worry about it until a few years down the road.

Harrington decided to follow the advice and wait. But when her 41st birthday approached this year, she felt uneasy. Her grandmother was 42 when her breast cancer was discovered so late in the course of the disease that it had spread all over her body.

Harrington kept thinking about that mammogram.

“For some odd reason this year, I was like man, I just feel like I want to go get one,” Harrington, who lives in Denver, Colorado, told TODAY.

“Honestly, I feel like maybe it was like a tap on my shoulder from (my grandmother).”

The diagnosis: stage 3 breast cancer that will require a bilateral mastectomy.

Harrington had no symptoms and felt nothing out of the ordinary in her body. She leads a healthy lifestyle that includes plenty of exercise as a fitness instructor and gym owner.

Sitting in shock after hearing the news at her doctor’s office in August, she was convinced the clinic must have had the wrong person’s chart, she recalled thinking.

“I’ve always done the right thing. I work out every day, I eat right, I try to take as good care of my body as I can, and cancer just doesn’t care,” she said. “It just doesn’t discriminate.”

Harrington owns two gyms in Denver and teaches classes. (Courtesy Teddy Sitorek)
Harrington owns two gyms in Denver and teaches classes. (Courtesy Teddy Sitorek)

She urged other women to get checked out even as the guidance on mammograms can be confusing, with different guidelines from different agencies.

The screening can find breast cancer early, but it can also show a spot that looks like cancer but is not, leading to unnecessary anxiety and invasive tests, the Centers for Disease Control and Prevention noted.

Another worry is overdiagnosis, or finding cancer that wouldn’t have gone on to cause any symptoms or problems.


The American Cancer Society recommends women with average breast cancer risk have an annual mammogram starting at 45; while the U.S. Preventive Services Task Force advises they can wait until 50 and have the test every other year.

Both agencies say women can choose to start annual breast cancer screening at 40 if they wish to do so.

Something about waiting until 45 “just sat with me wrong,” Harrington said, noting she had no pushback when she requested her first mammogram at 41. The clinic had minimal scheduling options because of the epidemic and she almost cancelled amid the busyness of her life, but decided to just check it off the list.

After getting the screening at the beginning of August, she was asked to come back for a second look. Her family and friends reassured her it was normal for the radiologist to want to get a different picture, but she knew it was serious when it turned out she’d also been scheduled for a breast ultrasound and a biopsy.



University Of Pittsburgh School Of Medicine Researcher Discovers How Coronavirus Causes Harmful Inflammation

PITTSBURGH (KDKA) — A researcher at the University of Pittsburgh School of Medicine has discovered how coronavirus can cause harmful and escalating inflammation.

It is because of a region on the spike protein she calls a superantigen.

“That region would be expected to trigger a very strong response, adaptive immune response, and now the response is so exaggerated,” says Ivet Bahar, Ph.D., distinguished professor and John K. Vries Chair of computational and systems biology at Pitt School of Medicine.

Her work came about by trying to get a better handle on what happens in the severe pediatric coronavirus-related illness MIS-C or multisystem inflammatory syndrome in children. The symptoms of low blood pressure, fever and rash looked very similar to toxic shock syndrome, a potentially fatal illness caused by bacterial toxins.

a close up of a hand

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By using computer models, she found a surprise.

“We started to compare the sequence and structure to existing superantigens, bacterial toxins, and found that there is a region that is very similar to a known bacterial toxin,” says Dr. Bahar.

This segment of the spike protein causes an excessive reaction in certain immune system cells and signals. This overreaction can lead to organ damage. Collaborators in Germany were able to show how her computer discovery actually happens in real-life patients.

“We know now that it’s not only children, we are observing the same phenomenon with also adults with severe COVID-19,” Dr. Bahar says.

But why it only happens in some people is still a mystery.

“Different people react in different ways somehow,” says Dr. Bahar. “That is something to further explore.”

The next step is to develop treatments to target the superantigen. Dr. Bahar hopes existing antibodies that target bacterial toxins might work.

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