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Serious coronavirus-related inflammatory condition among children now reported in adults: CDC

A rare but serious coronavirus-related inflammatory condition in children was also recently identified among adults, per a report released Friday from the Centers for Disease Control and Prevention (CDC).

Multisystem inflammatory syndrome in children (MIS-C) usually involves shock, heart malfunction, stomach pain and hyperinflammation. The CDC drew on reports of 27 adult patients to describe a new, similar condition —  multisystem inflammatory syndrome in adults (MIS-A).


“These 27 patients had cardiovascular, gastrointestinal, dermatologic, and neurologic symptoms without severe respiratory illness and concurrently received positive test results for SARS-CoV-2…,” per the report. Fortunately, the vast majority (24 of 27) of MIS-A patients survived, which was said to mirror outcomes seen in MIS-C patients treated in intensive health care settings.

There is still much unknown over MIS-A, with a deal of uncertainty over the timeline from SARS-CoV-2 infection to MIS-A onset, but the report suggests “MIS-A and MIS-C might represent postinfectious processes.” Adults who reported typical COVID-19 symptoms went on to develop MIS-A about two to five weeks later.

Patients with MIS-A may not test positive for COVID-19, given the onset of the syndrome weeks later. The agency emphasized the importance of antibody testing for previous SARS-CoV-2 infection to recognize and treat MIS-A.

Of the 27 MIS-A patients included in the report, 30% of them, along with “45% of 440 children with MIS-C reported to CDC through July 29,” tested negative for current SARS-CoV-2 infection but had positive antibody results.

There is still much unknown over MIS-A, a newly identified coronavirus-related complication in adults that had previously been reported among children. (iStock)

There is still much unknown over MIS-A, a newly identified coronavirus-related complication in adults that had previously been reported among children. (iStock)


The criteria used to identify MIS-A include severe illness requiring hospitalization in patients over age 21; current or previous SARS-CoV-2 infection in the past 12 weeks; severe dysfunction of one or more organs other than the lungs; lab evidence of severe inflammation and a lack of severe respiratory illness.

Patients were mostly treated with corticosteroids among other treatments like vasopressors (to raise blood pressure) or blood thinners.

The report also noted that “all but one” of the patients in the report were among racial or ethnic minorities, adding that “MIS-C has also been reported disproportionately in these communities.” However, due to the small sample size, the CDC said more research is needed before making conclusions about the burden of MIS-A in various groups.

“Findings indicate that adult patients of all ages with current or previous SARS-CoV-2 infection can develop a hyperinflammatory syndrome resembling MIS-C,” authors wrote, adding that measures to limit COVID-19 spread may help prevent MIS-A.


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Maryland records no coronavirus-related deaths for the first time in six months

Gov. Larry Hogan (R) said the drop was a positive step in the state’s battle against the pandemic, but he urged Maryland residents to remain vigilant and to continue taking health precautions.

“This encouraging milestone is a tribute to the incredibly heroic efforts of our doctors, nurses and health care workers on the front lines, and the courage and perseverance Marylanders have demonstrated in response to this unprecedented challenge,” he said in a statement.

Other virus-related metrics in Maryland on Thursday painted a mixed picture.

The state reported 785 new coronavirus cases — the highest in a single day since Sept. 12. The daily total was well above Maryland’s seven-day rolling average of new cases, which stood Thursday at 530.

It’s the sixth consecutive day that Maryland’s average number of cases has risen after dropping to 461 daily cases about a week ago. Meanwhile, the state’s coronavirus test positivity rate stands at 2.88 percent, which is a slight increase when compared with earlier in the week.

D.C., Maryland and Virginia on Thursday reported 1,267 new infections and 21 additional fatalities. Virginia had 450 new cases and 20 deaths, while D.C. had 32 new cases and one death. Both jurisdictions have seen a slight decline in caseloads in recent days.

The seven-day average of new cases in D.C., Maryland and Virginia stands at 1,313, down from more than 2,000 about two months ago. Health experts have cautioned that numbers could rise as chillier weather causes outdoor activities to shift indoors.

As economic fallout from the pandemic continued, Labor Department numbers released Thursday showed 21,456 people in Maryland, Virginia and D.C. filed for unemployment benefits last week, up from 17,792 a week earlier. More than 1.5 million residents in the Washington region have sought jobless benefits since the start of the pandemic.

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The Latest: UNC Reports Coronavirus-Related Student Death | World News

RALEIGH, N.C. — The University of North Carolina system reported its first coronavirus-related student death on Tuesday since several campuses reopened with at least partial in-person learning last month.

Chad Dorrill, a 19-year student at Appalachian State University who lived off campus in Boone and took all of his classes online, died on Monday due to coronavirus complications, officials said.

“Any loss of life is a tragedy, but the grief cuts especially deep as we mourn a young man who had so much life ahead,” said a statement from Peter Hans, chancellor of the system overseeing the state’s 16 public colleges and universities. “I ache for the profound sadness that Chad Dorrill’s family is enduring right now. My heart goes out to the entire Appalachian State community.”

The university reported a new high of 159 current COVID-19 cases among students on Tuesday. Nearly 550 students have tested positive for the virus since in-person classes resumed last month. Appalachian State remains open for in-person instruction.

Three North Carolina colleges, including UNC-Chapel Hill, North Carolina State University and East Carolina University, have halted physical classes for undergraduate students, after reporting a series of coronavirus outbreaks shortly after students returned to campus.


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— The coronavirus is infecting a rising number of American children and teens in a trend authorities say appears driven by school re-openings, resumption of sports and play dates.

— University of Notre Dame president Rev. John I. Jenkins apologized for not wearing a mask after pictures surfaced online of him shaking hands and sitting shoulder-to-shoulder with people at a recent Rose Garden ceremony.

— Tennessee Titans players, staff test positive for coronavirus; first outbreak in the NFL at Week 4.

Follow AP’s pandemic coverage at and


O’FALLON, Mo. — The number of people hospitalized for the coronavirus has nearly tripled in areas outside of Missouri’s two largest metropolitan areas since the state reopened for business in mid-June, according to state health department data Tuesday.

The Missouri Department of Health and Senior Services’ COVID-19 dashboard shows the state’s northwest, southeast, southwest and central regions all reached record highs for virus-related hospitalizations on Monday, based on seven-day averages. All told, Missouri reported 1,094 hospitalizations, five fewer than a day earlier, when statewide hospitalizations peaked.

Excluding the St. Louis and Kansas City areas, hospitalizations have risen 186% in the 3½ months since Republican Gov. Mike Parson allowed Missouri to reopen on June 16. The seven-day average for hospitalizations outstate on June 16 was 161; on Monday it was 461.

LIMA, Peru — Health workers for Peru’s