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Scientists confirm Nevada 25-year-old got coronavirus twice, second case was more severe

Scientists have confirmed the first case of coronavirus reinfection in the United States: a 25-year-old Nevada man whose second round of the virus was more severe than the first. 

The findings were published Monday in the medical journal The Lancet.

The man, who remains unnamed, first tested positive in April before recovering and testing negative in May. Then in June, he tested positive for the virus again, developing symptoms of COVID-19 a second time. 

According to the case study, his second infection included more severe symptoms than the first time around, including fever, cough and dizziness. 

The researchers sequenced the RNA from both virus samples and found they were two different strains, making it a true reinfection.

Scientists have not concluded why someone might contract the virus twice or if some people are more predisposed to reinfection. The Nevada case marks the fifth case globally of reinfection, and scientists say so far that instances are rare.

Yale University immunobiology professor Akiko Iwasaki told NPR a second positive test could happen for a number of reasons, including being exposed at higher levels to the virus or an immune response making the virus seem worse rather than better the second time around.

Generally, researchers are finding that people who get COVID-19 develop a healthy immune response, but it’s unknown how long it lasts. 

The case study was first sent to The Lancet in August, but it was officially published and the case was confirmed as the first U.S. reinfection this week.  

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A Nevada man got COVID-19 twice. His case shows why we need a vaccine

FILE - In this Monday, May 25, 2020 file photo, a vile of a COVID-19 vaccine candidate on a shelf during testing at the Chula Vaccine Research Center, run by Chulalongkorn University in Bangkok, Thailand. Refrigeration, cargo planes, and, above all, money: All risk being in short supply for the international initiative to get coronavirus vaccines to the world's most vulnerable people. (AP Photo/Sakchai Lalit, File)
A vial of an experimental COVID-19 vaccine. A new report that confirms a case of coronavirus reinfection underscores the need for a vaccine to achieve herd immunity, researchers say. (Sakchai Lalit / Associated Press)

If you were counting on a coronavirus infection to keep you safe from COVID-19 without having to get a vaccine, scientists have some bad news: It won’t work.

The evidence for this comes from a Nevada man who was infected with two distinct versions of the novel coronavirus and became sick with COVID-19 both times. In fact, he was sicker the second time around and had to be admitted to a hospital so that doctors could give him extra oxygen to help him breathe.

The unidentified patient is the first confirmed case in North America of a person being reinfected with the virus known as SARS-CoV-2, according to a report published Monday in the medical journal Lancet Infectious Diseases.

At first glance, the Nevada man wouldn’t seem to be a likely candidate for a case of COVID-19, let alone two. He was young — only 25 — and had no history of underlying medical conditions that would increase his risk of illness, the report authors wrote. He wasn’t taking any drugs that could have suppressed his immune system. Blood tests showed he was HIV-negative, and his cell counts all appeared normal, they added.

But on March 25, he started coming down with an ominous list of symptoms: sore throat, cough, headache, nausea and diarrhea. By April 18, they’d become bad enough that he went to a coronavirus testing center run by the Washoe County Health District. Workers obtained a specimen from the back of his nasal cavity. Sure enough, it contained genetic evidence of SARS-CoV-2.

The man recovered in isolation at home, and his symptoms cleared up nine days later. Two follow-up tests, on May 9 and May 26, confirmed he was negative for coronavirus infection.

That should have been the end of the story. But on May 28, he started to feel sick again.

By May 31, he went to an urgent care center complaining of a fever, headache, dizziness, cough, nausea and diarrhea. He got a chest X-ray and was sent home.

On June 5, he was having trouble breathing, and his body wasn’t getting enough oxygen to his tissues. He went to see his primary care doctor, who sent him to a hospital. Another chest X-ray indicated he had pneumonia, and he was admitted and treated with supplemental oxygen.

Once again, a nasopharyngeal coronavirus test came back positive.

Was it the same case of COVID-19, or did he have the disease twice?

Repeat coronavirus infections are thought to be rare, but they have been confirmed in patients in Hong Kong, Belgium and Ecuador. A team led by biostatistician Richard Tillett of the Nevada Institute of Personalized Medicine went to great lengths to see whether the Washoe County patient should be added to that list.

The fact that his positive coronavirus tests

Confirmed Coronavirus Case Total In Baltimore County At 19,043

BALTIMORE COUNTY, MD — As of Monday, Baltimore County has a total of 19,043 positive new coronavirus cases, according to the Baltimore County Health Department, and 622 deaths. The state has 116,646 confirmed cases and 3,696 deaths total, reports the Maryland Department of Health. More than 14,884 people have been hospitalized.

The number of confirmed cases in Baltimore County nursing homes stands at 717. The number of death cases in Baltimore County nursing homes is at 104.

The following zip codes have the highest confirmed case counts in Baltimore County as of Oct. 12:

  • 21222 with 1,411 cases

  • 21234 with 1,364 cases

  • 21117 with 1,258 cases

  • 21228 with 1,297 cases

  • 21220 with 1,114 cases

The county health department has its own website created to monitor the situation, broken down by new cases per day and other data.

The CDC advises doing the following to stop the spread of the virus:

  • Wash your hands often with soap and water for at least 20 seconds. If this is not available, use hand sanitizer that is at least 60 percent alcohol.

  • Clean and disinfect frequently touched objects and surfaces.

  • Keep 6 feet of space between people.

  • Stay home when you are sick.

  • Cover your cough or sneeze with a tissue, then throw the tissue in the trash.

This article originally appeared on the Catonsville Patch

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2020 Heart of Case Management Awards

Winners of preeminent case management award show resilience during an unprecedented year

In a year when pandemic restrictions put the world on pause, Genex Services’ case managers kept going, determined to help injured employees regain function and return to work in a timely manner. Such successful acts of perseverance resonated in each nomination received for the 5th annual Heart of Case Management Awards and the four winning cases selected for this year’s honors reflect the best of these individual acts of excellence.

This press release features multimedia. View the full release here:

Held this year in conjunction with National Case Management Week (Oct. 11-17), the Genex Heart of Case Management Award recognizes four case managers who have made the greatest impact on the injured employees they served. Now in its fifth year, the Heart of Case Management Awards is a national program recognizing Genex case managers who are highly regarded for transcending beyond their traditional job duties to improve the lives of thousands of injured employees each year. The four winners were nominated from a field of more than 1,600 Genex case managers across the country and judged on the following criteria: specialist, excellence, adaptability, trust, influential communication and outcomes.

Among this year’s winners is a case manager who worked tirelessly to keep a homeless injured employee off the streets so she could recover and avoid contracting COVID, another who advocated for an amputee to receive a highly functional hand prosthetic to return to full duty and a bilingual case manager who broke down cultural barriers to help four employees who sustained serious burns get the care they needed to heal and get back to their jobs.

Watch this video to see how case managers moved claims forward during COVID-19.

The following are synopses of the winning entries.

Catastrophic Case Management
Kayla Payne, RN, BSN, CCM
Memphis, TN
A 45-year old man working on a conveyer accidentally had his hand get stuck in an augur. The immense trauma he experienced was intensified by the tenuous process of safely releasing his hand from the machine — a 30-minute ordeal. Finally freed, the man was rushed to the local emergency department (ED) where he was diagnosed with a crush injury. Payne was assigned to the case and met the injured employee at the hospital. A hand surgeon was called in and it was determined the man would require below-elbow amputation of his left arm. Prior to becoming a case manager, Payne had worked as an ED nurse at the same hospital where the man was being treated. Her experience and relationships with medical staff allowed her to quickly report the necessary information to the adjuster to begin the treatment plan. After extensive surgery, Payne developed a return-to-work plan, communicating realistic outcomes to the adjuster and the employer. When the specialist recommended the injured employee be fitted with an electrical hand and a gripper prosthesis, Payne became educated on the prosthesis, so she could address the injured employee’s questions and concerns. Through

Coronavirus live updates: Mexico confirms 1st case of someone with both COVID-19 and influenza

There were 44,614 new cases of COVID-19 identified in the United States on Sunday, according to a real-time count kept by Johns Hopkins University.

The latest daily tally is down by more than 10,000 from the previous day and falls well under the country’s record set on July 16, when there were 77,255 new cases in a 24-hour-reporting period.

An additional 400 coronavirus-related fatalities were also recorded Sunday, down from a peak of 2,666 new fatalities reported on April 17.

A total of 7,762,809 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 214,771 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.

By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country’s cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 70,000 for the first time in mid-July. The daily tally of new cases has gradually come down since then but has started to climb again in recent weeks.

Week-over-week comparisons show the number of new cases reported across the nation continues to go up, as does the usage of intensive care units, but the number of new deaths are down, according to an internal memo from the U.S. Department of Health and Human Services that was obtained by ABC News last week.

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Frenchman in right-to-die case to stop food, medicine

Issued on:

Dijon (France) (AFP)

A terminally ill Frenchman who had planned to live stream his death on social media told AFP Saturday that he would refuse all food and medication “until the very end”.

Alain Cocq, 57, had earlier announced he was refusing all food, drink and medicine from September 5 after French President Emmanuel Macron turned down his request for euthanasia.

But he accepted palliative care after refusing food and medication for over three days because the pain had become unbearable.

“From midnight on Monday, October 12, I will stop all hydration, food and treatment apart from painkillers,” he told AFP.

“I will go right till the end.”

Cocq suffers from a rare genetic condition which causes the walls of his arteries to stick together.

He has used his plight to draw attention to the situation of terminally ill patients in France who are not allowed to die in line with their wishes.

Cocq said that when he had accepted palliative care after his abortive first attempt, the medical emergency team had to put him back on hydration and food for the pain killers to work.

He said he had drawn a lesson from that.

“This time round, I will put my wish in writing … even if I seek medical aid at a given moment, it does not mean I wish to live.

“It would mean that I cannot bear the suffering any longer and that I seek a deep and continued sedation,” he said.

Right-to-die cases have long been an emotive issue in France.

Most polarising was the case of Vincent Lambert, who was left in a vegetative state after a traffic accident in 2008 and died in July last year after doctors removed life support following a long legal battle.

The case divided the country as well as Lambert’s own family, with his parents using every legal avenue to keep him alive but his wife and nephew insisting he must be allowed to die.

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State reports second-highest case count ever

The state of Wisconsin is reaching a crisis point in the COVID-19 pandemic. 

a person in a car: Free testing being done the Wisconsin Army National Guard at the Winnebago County Health Department's new regional COVID-19 testing site on Wednesday, Sept. 2, 2020, at the Sunnyview Expo Center in Oshkosh.

© Wm. Glasheen/USA TODAY NETWORK-Wisconsin
Free testing being done the Wisconsin Army National Guard at the Winnebago County Health Department’s new regional COVID-19 testing site on Wednesday, Sept. 2, 2020, at the Sunnyview Expo Center in Oshkosh.

Particularly in northeastern Wisconsin, hospitals are filling up and cases continue to spiral out of control. Follow our updates on the impact of COVID-19 in the Milwaukee area and around the state of Wisconsin.

BY THE NUMBERS: Tracking coronavirus cases in Wisconsin

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RELATED: Cases around the United States and world

5:45 p.m.: Wisconsin Hospital Association forms coalition

The Wisconsin Hospital Association and a coalition of health care and business organizations have formed a coalition to encourage people to wear masks and take other precautions to check the surge in COVID-19 infections in the state.

“What we know is that masks work,” said Eric Borgerding, president and CEO of the Wisconsin Hospital Association. “And whether it’s through a mandate or through very vigilant use and encouragement of using masks, we know that it works.”

The planned campaign comes at a time when the state has seen a record number of COVID-19 cases and deaths from the coronavirus.

Borgerding did not comment on the opposition by Republican leaders of the state Legislature to Gov. Tony Evers’ statewide mandate requiring people to wear masks in public places when not a safe distance from others.

Read the full story from Guy Boulton.

5 p.m.: State reports second-highest coronavirus case count ever

Wisconsin on Friday reported 2,988 new coronavirus cases — the second-highest daily total ever, behind only Thursday’s record-shattering case count of more than 3,000.

The state Department of Health Services also reported 16 deaths due to the virus, bringing the death toll to 1,440.

The massive volume of cases reported since early September has had a significant impact on Wisconsin’s burgeoning health crisis.

Of the more than 144,000 confirmed cases in Wisconsin since the pandemic began, nearly half have come since Sept. 1, according to a Milwaukee Journal Sentinel analysis.

In the first eight months of the year, Wisconsin reported about 75,000 cases. In the roughly six weeks since Sept. 1, it has reported about 69,000 cases.

Read the full story from Sophie Carson here.

2:12 p.m.: Oconto County feeling strain of virus spread, hospitalizations 

Oconto County Public Health officer Debra Konitzer called on residents act to stop the spread of COVID-19.

The “uncontrolled spread” has led to an increase in hospitalizations and is straining health care systems, which are operating at crisis capacity, according to a statement Friday from Konitzer, Christopher Brabant, president and CEO of HSHS St. Clare Memorial Hospital, and James Dietsche, CEO of Bellin Health Oconto.

“It is extremely important that our communities remain vigilant in their actions and how they contribute to the spread of COVID-19,” Brabant said. “If you are experiencing symptoms of COVID-19 or have been

Trump gives overview of COVID-19 case in first on-camera interview since diagnosis

President TrumpDonald John TrumpBiden campaign raises over M on day of VP debate Trump chastises Whitmer for calling him ‘complicit’ in extremism associated with kidnapping scheme Trump says he hopes to hold rally Saturday despite recent COVID-19 diagnosis MORE on Friday participated in his first on-camera interview since testing positive for COVID-19, during which he admitted that he remained hospitalized for observation after scans showed some congestion in his lungs and touted the benefits of his early treatment.

The president offered a rosy outlook of his path forward in a pre-recorded interview with Fox News medical contributor Marc Siegel. Trump spoke to Siegel from the Rose Garden, while the doctor was based in a network studio.

Trump insisted that he was feeling well and that he had been “medication free” since earlier in the day. But he acknowledged that he experienced fatigue and could have faced a more dire outcome without the access to medical care he has as president.

“They tested the lungs, they checked for the lungs and they tested with different machinery … and it tested good,” Trump said of his stay at Walter Reed National Military Medical Center. “Initially I think they had some congestion in there, but ultimately it tested good. And with each day it got better, and I think that’s why they wanted me to stay.”

The president also reported feeling fatigued after contracting the virus. While he did not discuss it on Friday, Trump also required supplemental oxygen, according to his physician, before being taken to the hospital.

The president — who has repeatedly downplayed the severity of the virus and falsely claimed that the disease affects “virtually” no young people — highlighted the importance of early treatment for combating COVID-19.

“The biggest thing is that I did do it early,” Trump said. “Now I have such great access to medical … so it’s a lot easier for me than somebody who doesn’t have access to a doctor so easily.”

“And, you know, I think it would have gotten a lot worse. One of the doctors said he thought it would have gotten a lot worse,” he added. “I just think that even these medications, they’re a lot better if you get them early than if you get them late. I think going in early is a big factor in my case.”

The president tested positive for COVID-19 on Oct. 1. He was taken to the hospital on Oct. 2, and he was discharged Oct. 5. Centers for Disease Control and Prevention (CDC) guidance advises that those infected with COVID-19 isolate for at least 10 days from the onset of symptoms, or longer in more serious cases.

Trump has repeatedly touted the benefits of an antibody cocktail he was given upon his diagnosis, calling it a “miracle” and a “cure.” But the treatment from Regeneron is still in the trial phase and is not widely available to the public.

Trump has politicized other treatments for the virus, including hydroxychloroquine, and pushed

Trump’s COVID case could be entering a crucial stage

Early in the morning on October 2, President Donald Trump tweeted that he had tested positive for COVID-19. Only 33 days away from a highly contentious election, the diagnosis plunged the nation into uncertainty. Doctors, scientists and pundits quickly began speculating on what will happen to the president, and the White House has been both tight-lipped and prone to giving conflicting information about the VIP patient.

But in general, the course of this disease is no longer a complete black box to medicine. Trump will be at a fork in the road during the latter half of this week, say infections disease and critical care physicians who spoke with Scientific American. He could be heading for a bad stretch in a prolonged illness or he could be on an upward swing to recovery. Doctors sadly have the experience of treating more than 36 million COVID-19 patients worldwide and more than 7.5 million in the U.S. Using this clinical history, many now divide the disease into several stages, each with distinct symptoms and treatments. Based on when he first reported symptoms, Trump appears to be at the end of one phase and the verge of the next. Here is the sequence that physicians usually see and how it applies to the president.

Exposure and incubation

A COVID-19 infection begins when the SARS-CoV-2 virus enters cells in the body and begins to replicate. This period of time, after infection but before symptoms start, is called the incubation period—and it occurs between two and 14 days after contracting the virus. While people may not know they are sick, they often become contagious two or three days before symptoms begin.

Viral replication

Symptoms start by the fifth day after infection for most people, and they include fever, cough, sore throat, fatigue, aches, pains, gastrointestinal issues, and loss of smell or taste. Taison Bell, a pulmonary and critical care physician at the University of Virginia, says that when symptoms arise, this change signals a person is at “peak infectivity,” which means they are shedding lots of virus particles into the air, putting nearby people at risk.

This timing has big implications for the president and those around him, Bell says: “The most famous person in the world right now has COVID-19, and one could assume, based on the time line, that he could have been infectious during the presidential debate.” The televised argument with challenger Joe Biden took place last Tuesday, and Trump began showing symptoms on the following Thursday. “He is still infectious now and was when he took his joyride,” says Bell, referring to short trip Trump took in a car with Secret Service agents on Sunday. The vehicle traveled around and just outside the Walter Reed National Military Medical Center, where he was being treated.

At this early stage of the disease, most people do not receive aggressive treatment, but Trump was given two experimental drugs: the antiviral medication remdesivir and an infusion of monoclonal antibodies. He also received an established

Senior Official Explains VP’s Health After Mysterious Case At Debate

A flurry of speculation has surrounded the health of Vice President Mike Pence after he appeared to have pink eye at Wednesday’s debate with Sen. Kamala Harris. A senior Trump administration official told Politico that Pence likely suffered from a broken blood vessel, rather than a pink eye infection. 

Pence’s eye problem, as well as a fly that settled on his head, drew attention on social media.

Dr. Daniel Volland, an optometrist based in Seattle, also diagnosed Pence with a broken blood vessel.

“Eye doctor, here! Temporal Subconjunctival Hemorrhage OS is my diagnosis; it’s a broken blood vessel, not infectious,” Volland tweeted. 

Although some debate viewers thought Pence’s eye could be a symptom of COVID-19, the vice president tested negative for the virus prior to the event. Pink eye is a rare symptom of a COVID-19 infection.

“The number of COVID-19 patients that have been reported to have eye symptoms is relatively low. And when you have a population that small, it’s really hard to get a picture of the story because we just don’t have as many data points,” optometrist Alexandra Williamson, OD, recently told the Cleveland Clinic. 

Pence’s health condition is noteworthy, due to President Donald Trump’s positive COVID-19 diagnosis. If Trump were to become incapacitated, Pence would likely have to take over presidential duties per the 25th amendment.

Numerous members of the Trump administration and campaign have been infected with the virus. First lady Melania Trump, campaign manager Bill Stepien, senior adviser for policy Stephen Miller, Press Secretary Kayleigh McEnany and former New Jersey Gov. Chris Christie are just a few high-profile members of Trump’s inner circle to test positive for COVID-19.

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