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Brazil coronavirus vaccine trials: Volunteers counter anti-vaxxers

“A two-front war,” she said.

It’s one reason the 33-year-old physician is participating in clinical trials for an experimental vaccine by the Chinese manufacturer Sinovac. It might be a chance to inoculate herself against a disease that terrified her. But it was also an opening to align herself with evidence and logic — rather than the doubts and medical falsehoods she saw proliferating across Brazil.

Brazil has long been recognized as one of the vaccine-friendliest countries in the world. It has universal health care, a strong public medical system, a population that has trusted vaccines and a history of carrying out massive and logistically challenging immunization campaigns. Yellow fever, measles and other pathogens have all been brought into submission.

That record, and a relentless coronavirus outbreak that has killed more than 150,000 Brazilians and infected more than 5 million, have made Brazil an inviting testing ground in the global race for a vaccine. Four of the leading vaccine candidates are being studied in the country. That’s as many as anywhere in the world. Tens of thousands of Brazilians have received trial vaccines to ensure their safety and efficacy before they’re approved for broader use.

But Brazil’s vaunted culture of vaccination is now coming under strain. The uncertainties unleashed by the coronavirus pandemic — amplified by social media and echoed by a polarizing president who has flouted health guidelines and promoted miracle cures — has rapidly eroded trust painstakingly built over decades.

In June last year, 97 percent of Brazilians said they believed in the importance of vaccinating children, according to an international a survey by the Wellcome Global Monitor. That figure was higher than the global average of 92 percent and higher than regional neighbors. But months into the country’s coronavirus outbreak, the number of Brazilians who say they would certainly get a coronavirus vaccine has fallen to 76 percent.

Bolsonaro, rather than rallying support for a vaccine, has undercut it.

“No one can force anyone to take a vaccine,” he has said.

Falling support for a vaccine, even as researchers plow ahead with trials, has worried scientists who say Brazil is at risk of losing faith in science at the most critical time. Many Brazilians are returning to old routines while the country is still in the full grip of the virus. It’s killing hundreds, sometimes more than 1,000, every day. Tens of thousands more fall ill.

“This is a decisive moment,” said João Henrique Rafael Junior, a researcher at the University of São Paulo. In a survey published last month, he found the number of social media posts in Brazil spreading doubt and misinformation about vaccines has nearly quadrupled since the beginning of the pandemic.

“We need to reverse the curve,” he said. “We are going through the worst health crisis in a century, and we need to employ all of our strength. The time is now. Actually, the time was yesterday.”

Natália Pasternak Taschner, a microbiologist, warned the conditions could lead to disaster.

“We are witnessing something

We Need One Million Volunteers for COVID-19 Vaccine Trials

We need one million more citizens to volunteer for the COVID-19 vaccine trials. Almost half a million Americans have signed up to be part of the clinical trials, but in order to complete the study, the COVID-19 Prevention Network—formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the U.S. National Institutes of Health—will need more volunteers, and especially more volunteers from diverse backgrounds. The sooner the clinical trials finish accruing patients the sooner we will have results of the vaccine studies.

I am a cancer doctor, but like many doctors and researchers have been called in to assist in any way we can to help the effort to fight COVID-19. We are all seeing too much suffering from this devastating virus. While there are many clinical trials across the country working on treatments for COVID-19 and prevention strategies, few are as important as our national vaccine effort. I teamed with David Ellison, a Hollywood producer, and his amazing team, as well as the incomparable Harrison Ford, to put together a public service announcement to encourage every citizen to consider enrolling in the vaccine trial effort.

To aid in this effort, the COVID-19 Prevention Network sent an email out to those that had already volunteered, asking them why they did it. What they received back was overwhelming: an outpouring of inspirational and emotional videos, each giving a personal reason for becoming part of the trials.

It’s inspiring that we have seen so many Americans come forward to help one another and be part of the solution to COVID-19. But, for the clinical trials to be completed, we need more volunteers. I am not a part of the COVID-19 Prevention Network, but am privileged to play my part to assist them fight this invisible enemy, and I so hope many others do the same.

Please see PreventCOVID.org for more information and to register for the trial.

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