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Boston research team says it has enrolled a diverse group in Moderna’s coronavirus vaccine study

The hospital is among 90 sites testing to see whether the prospective vaccine made by Moderna is safe and protects people against the coronavirus. The Cambridge biotech’s vaccine is among 11 candidates worldwide that have entered late-stage clinical trials.

“We want our study and enrollment to be representative of the epidemic and the communities disproportionately impacted,” said Baden, who is also one of three leaders of the national study.

Since the study began in the first week of August, Brigham and Women’s has recruited “many hundreds” of participants, he said, adding that he was not free to say exactly how many. Recruitment is continuing and is likely to be completed in “weeks, if not sooner,” Baden said.

Half the participants enrolled nationwide will receive the vaccine candidate, and half will get a placebo, in two injections 28 days apart. Then researchers will watch to see if those who received the vaccine are less likely to get infected. The majority of the Boston participants have received both injections, Baden said.

Some 40 percent of the Boston enrollees are people with health conditions that put them at higher risk of severe infection, and more than 25 percent are elderly, Baden said.

Moderna, like all of the other vaccine makers, wants to make sure it gathers adequate information on the vaccine’s effectiveness among the people most affected by the epidemic, which has disproportionately struck people who are Black and Latino, as well as those with underlying conditions such as heart or lung disease.

Nationwide, the Moderna study has enrolled 28,000 of the 30,000 participants needed to evaluate the vaccine, and 33 percent identify as nonwhite, according to a statement from the company.

The company did not provide a breakdown of which groups are represented in the 33 percent, but Reuters reported earlier this week that 7 percent of enrollees are Black.

Black people comprise 12.3 percent of the nation’s population and 21.1 percent of those who died of COVID-19, according to a recent analysis by National Public Radio. Latino people account for 17.8 percent of the population and 21.1 percent of COVID-19 deaths, NPR found.

Moderna has urged the clinical sites “to further emphasize outreach to diverse populations, even if those efforts impact the speed of enrollment,” its statement said. A spokesperson said these efforts have led to “a modest delay in enrollment completion” but probably will not affect the timing of initial results.

Meanwhile, Moderna’s weekly enrollment data show improvements in recruiting diverse participants; among those who signed up during the week of Sept. 28, 49 percent were Hispanic or Latino people, and 26 percent were Black people.

At Brigham and Women’s, the study team has drawn upon long-established relationships in communities hardest-hit by COVID-19, said Dr. Paulette Chandler, who is leading community education and engagement for the vaccine trial.

“People trust us because they come to us for health care,” she said. The hospital also has a community advisory board established during its decades of work on HIV vaccines. “They served

54 Dentists Supported By 42 North Dental Receive “Top Dentist” Awards In Annual Boston Magazine Guide | News

BOSTON, Oct. 1, 2020 /PRNewswire/ — 42 North Dental, a leading dental support organization in the Northeast, announced today that 54 of their supported dentists have been awarded the honor of “Top Dentist” in Boston Magazine’s “Top Dentists in Boston” Guide, 2020. 54 is a record number of wins for any dental practice in a single year. In total, since program inception, 42 North Dental has had more “top dentist” wins than any other dental practice in the coverage area.

“I’m proud of the winning dentists and their colleagues across the company.” says Dr. Michael Scialabba, 42 North Dental Vice President of Clinical Affairs. He continues “To have other dentists in our region vote 42 North Dental dentists as ‘top dentists’ further proves our message that group dentistry, and our model, leads to exceptional patient care.”

As a member of 42 North Dental, dentists are able to focus their time and effort on maintaining positive relationships with their patients and providing expert care, rather than the business burdens that come with running a dental practice. As part of a large network of dentists, they are also able to effectively collaborate on best practices, pooling their knowledge and expertise.

And the Winners are:

Roua al Timimi – General Dentistry, Gentle Dental Quincy; Marissa Alikpala – General Dentistry, Gentle Dental Arlington; Saishree Amin – General Dentistry, Gentle Dental Wakefield, Marjan Askari – Orthodontics, Gentle Dental Arlington, Belmont, Boston, Milford, Natick, Newton, South Boston, Waltham; John Brangan – General Dentistry, Great Hill Dental Somerville; David Buczak – Endodontics, Gentle Dental South Attleboro, Saugus; Hannah Cohen – Endodontics, Gentle Dental Somerville, Wakefield, Waltham; Jose Oscar Colon – Periodontics, Gentle Dental Derry, Jamaica Plain, Nashua, Wakefield; Yonathon Dassa – General Dentistry, Gentle Dental Brookline; Leena Desai – General Dentistry, Gentle Dental Chelmsford; Ian Fessler – General Dentistry, Gillis Dental; Matteo Giamarco – General Dentistry, Gentle Dental Peabody, Robert Girschek – General Dentistry, Gentle Dental Waltham; David Goldberg – Periodontics, Abington Family Dental Care, Newbury Dental Associates, Gentle Dental Cambridge, Natick, Waltham, Worcester; Lawrence Goodman – General Dentistry, Great Hill Dental Braintree; Erin Hersey – General Dentistry, Dynamic Dental; Matthew Hickin – Periodontics, Gentle Dental Brookline, Malden, Methuen, South Boston, Great Hill Dental Peabody, Somerville; Natalia Hoffmann – Orthodontics, Gentle Dental Brighton, Jamaica Plain, Malden, Peabody, Wakefield, West Roxbury; Yong Hur – Periodontics, Great Hill Dental Boston; Maryanne Irwin – Endodontics, Great Hill Dental Boston, Braintree, ; Jennifer Kim – Endodontics, Gentle Dental Braintree, Brighton, Milford, New Bedford, Quincy, Worcester; Kirill Klimashov – Oral Surgery, Gentle Dental Arlington, Cambridge, Natick, Norwood, Somerville, Waltham, West Roxbury, Worcester; Ibrahim Lakkis – Oral Surgery, Attleboro, Braintree, Brookline, Jamaica Plain, Quincy; Ryan Lee – General Dentistry, Great Hill Dental Boston; Cheri Li – General Dentistry, Gentle Dental Cambridge;

54 Dentists Supported By 42 North Dental Receive “Top Dentist” Awards In Annual Boston Magazine Guide

“I’m proud of the winning dentists and their colleagues across the company.” says Dr. Michael Scialabba, 42 North Dental Vice President of Clinical Affairs. He continues “To have other dentists in our region vote 42 North Dental dentists as ‘top dentists’ further proves our message that group dentistry, and our model, leads to exceptional patient care.”

As a member of 42 North Dental, dentists are able to focus their time and effort on maintaining positive relationships with their patients and providing expert care, rather than the business burdens that come with running a dental practice. As part of a large network of dentists, they are also able to effectively collaborate on best practices, pooling their knowledge and expertise.

And the Winners are:

Roua al Timimi – General Dentistry, Gentle Dental Quincy; Marissa Alikpala – General Dentistry, Gentle Dental Arlington; Saishree Amin – General Dentistry, Gentle Dental Wakefield, Marjan Askari – Orthodontics, Gentle Dental Arlington, Belmont, Boston, Milford, Natick, Newton, South Boston, Waltham; John Brangan – General Dentistry, Great Hill Dental Somerville; David Buczak – Endodontics, Gentle Dental South Attleboro, Saugus; Hannah Cohen – Endodontics, Gentle Dental Somerville, Wakefield, Waltham; Jose Oscar Colon – Periodontics, Gentle Dental Derry, Jamaica Plain, Nashua, Wakefield; Yonathon Dassa – General Dentistry, Gentle Dental Brookline; Leena Desai – General Dentistry, Gentle Dental Chelmsford; Ian Fessler – General Dentistry, Gillis Dental; Matteo Giamarco – General Dentistry, Gentle Dental Peabody, Robert Girschek – General Dentistry, Gentle Dental Waltham; David Goldberg – Periodontics, Abington Family Dental Care, Newbury Dental Associates, Gentle Dental Cambridge, Natick, Waltham, Worcester; Lawrence Goodman – General Dentistry, Great Hill Dental Braintree; Erin Hersey – General Dentistry, Dynamic Dental; Matthew Hickin – Periodontics, Gentle Dental Brookline, Malden, Methuen, South Boston, Great Hill Dental Peabody, Somerville; Natalia Hoffmann – Orthodontics, Gentle Dental Brighton, Jamaica Plain, Malden, Peabody, Wakefield, West Roxbury; Yong Hur – Periodontics, Great Hill Dental Boston; Maryanne Irwin – Endodontics, Great Hill Dental Boston, Braintree, ; Jennifer Kim – Endodontics, Gentle Dental Braintree, Brighton, Milford, New Bedford, Quincy, Worcester; Kirill Klimashov – Oral Surgery, Gentle Dental Arlington, Cambridge, Natick, Norwood, Somerville, Waltham, West Roxbury, Worcester; Ibrahim Lakkis – Oral Surgery, Attleboro, Braintree, Brookline, Jamaica Plain, Quincy; Ryan Lee – General Dentistry, Great Hill Dental Boston; Cheri Li – General Dentistry, Gentle Dental Cambridge; Andrew Mancini – General Dentistry, Gentle Dental Jamaica Plain; Jonathan Millen – General Dentistry, Newbury Dental Associates; Catherine Moshirfar – Periodontics, Great Hill Dental Boston; Cassandra Myer – General Dentistry, Gentle Dental Brighton; Jake Park – Periodontics, Gentle Dental Braintree, Burlington, Chelmsford; Shimul Patel – General Dentistry, Gentle Dental Natick; David Pawlowski, Great Hill Dental Boston; Stephanie Payne– General Dentistry, Gentle Dental Malden; Joseph Purman – General Dentistry, Great Hill Dental Boston; Marisa Reason – Orthodontics, Dynamic

Boston Coronavirus Cases Surge, City Added To 23 ‘High Risk’ Zones

KEY POINTS

  • Boston and 10 other Massachusetts cities have been listed as coronavirus red zones
  • State health officials reported more than 8 cases per 100,000 residents over the past 14 days
  • 23 municipalities in Massachusetts are considered “high risk” for COVID-19 infection

Boston and 10 other Massachusetts cities have been listed as red zones or “high risk” areas as of Wednesday night as a sudden spike in the number of cases bring the state’s total to 128,753.

According to Boston News, health officials from the Department of Public Health reported more than eight cases per 100,000 residents over the past two weeks. They also confirmed 32 new COVID-19 casualties, which brings Massachusetts’ death toll up to 9,242. 

In all, 23 municipalities in the state are considered “high risk” for coronavirus infection. The new communities joining Boston on the list are Attleboro, Avon, Dracut, Haverhill, Lowell, Lynnfield, Methuen, Middleton, North Andover, and Springfield. 

Health officials also moved three communities—Saugus, Tyngsborough, and Wrentham—to moderate risk as their infection rates continue to experience a drop. 

Before the release of the report, Boston Mayor Marty Walsh said the city was not moving into the second step of its three-phase reopening plan due to the surge of coronavirus cases. 

“We expect to be in the red zone very soon, and it is likely to happen this evening. That means we’ve been seeing more than eight new cases per day per 100,000 people population,” Walsh said Wednesday.

During a press conference, Walsh noted that half of the new cases reported in the city involved people aged 29 and younger. He also said the city would maintain its coronavirus restrictions to curb the virus’s spread, WBUR reported.

Food courts may continue to operate, and movie theaters may go to a 50% capacity and limit their audience to 250 people. Gatherings will be limited to 25 people for indoor events and 50 for outdoor affairs. 

According to WCVB, public school students in Boston will begin returning to classrooms Thursday, depending on their grade level and academic needs. The highest-need students will be the first to transition using a hybrid model. 

Pre-schoolers and kindergartners would be required to report to school in the second week of October, while first- and third-graders would follow the week of Oct. 22.

Under the hybrid model, students are to learn in-person for two days a week and switch back to remote-learning the other three days of school. Families are given the option to keep their children remote. 

Madrid has seen a surge in coronavirus cases in Spain's second wave Madrid has seen a surge in coronavirus cases in Spain’s second wave Photo: AFP / OSCAR DEL POZO

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